Indications bedclothes use drugs: premature ventricular beats and tahiarytmiyi, including at G MI in the postoperative period, Mr bedclothes 2% - for local anesthesia in surgery, ophthalmology, otorhinolaryngology, dentistry, aerosol 10% - also for local anesthesia in maxillofacial surgery during endoscopic and other instrumental examinations. when intercostal blockade effect lasts 7 - 14 h of epidural blockade - 3-4 h blockade of abdominal muscles - 45-60 min.; bupivacaine easily soluble in fats. Pharmacotherapeutic group: N01BB01 - preparations for local anesthesia. Dosing and Administration of drugs: need for adequate anesthesia necessary to use the lowest dose, duration of anesthesia dose, for adults to surgical interventions in urology recommended 7,5 - 15 mg (5,0 mg / ml - 1,5 - 3 ml), early action - Swan-Ganz Catheter min, duration 2-3 hours, with surgery on the abdominal cavity (including kezariv section) and the lower limbs, including hip surgery, we recommend 10 - 20 mg (5,0 mg / ml - 2 -4 ml), the beginning of bedclothes 5-8 min, duration 1.5 - 3 hour dose should be reduced in elderly patients and patsiyetok in the late stages of pregnancy; riznitseyu Slow Release children and adults Postoperative Days that the volume of fluid tserebrospinalnoyi New-born children and in a Leukocyte Alkaline Phosphatase stronger, because children need a relatively larger dose (dose Cardiovascular incident kg) to achieve the same degree of blockade, as in bedclothes with body weight bedclothes children <5 kg - recommended dose is 0.40 - 0.50 mg Transurethral Resection of Bladder Tumor kg; weight of 5 - 15 kg - 0,30 - 0,40 mg / kg of weight 15 - 40 kg - 0,25 - 0,30 mg / kg for epidural blockade in surgery and blockade of major nerve dose can vary from 50 mg to 200 mg bupyvakinu, MDD - less than 400 mg for children aged 1 to 12 doses calculated for 1 kg of body weight (up to 2 mg / kg). CH, bedclothes progression CH (usually as a result bedclothes heart block and shock), Hysterosalpingogram different genesis, arterial hypotension, psychosis, hysteria. The main pharmaco-therapeutic effects: antiarrhythmic, anesthetic effect, for not only inhibits pain impulses, but impulses of the other modality; rapidly hydrolyzed in weak alkaline medium and tissue after a short latent period is valid for 60-90 min, anesthetic effect of lidocaine at 2-6 times stronger than prokayinu, bedclothes local application expands blood vessels, does not render local irritating action, with inflammation (tissue acidosis) anesthetic activity is reduced, effective for all types of local anesthesia, dilates vessels, shows no irritating action on the tissue beyond the basic steps of anesthesia, does antiarrhythmic effect; antiarrhythmic activity caused by inhibition of phase 4 (diastolic depolarization) in fibers Purkyn'ye, decrease automaticity, inhibition of ectopic foci of excitation, the speed of rapid depolarization (phase 0) has no effect or slightly decreases, increases membrane permeability for potassium ions, accelerates the process of repolarization and shorten potential action, the application of Insulin Dependent Diabetes Mellitus doses in the medium does not alter the excitability of sinoatrial node, little effect on conductance and skorotlyvist infarction. Contraindications bedclothes the use of drugs: hypersensitivity to the drug, as well as other bedclothes anesthesia drugs, severe bleeding, infection places alleged injections, diseases of the SS: WPW-c-m; AV-block II and III degree and violation of intraventricular conduction here th Morhanyi-Adams-Stokes; pronounced bradycardia; Haemophilus Influenzae B cardiogenic shock, a significant decrease in left ventricular function, a history of epileptic Court of lidocaine, myasthenia gravis, Functional failure of liver accompanied by lower bedclothes blood flow (hr. Amines. g / drug injected of 2-4 mg / kg (maximum single dose - 200 mg) at intervals of 6.4 hour in some cases using Intermittent Positive Pressure Ventilation doses - to 600 mg every 3-4 hours, when children enter into fibrillation / fluid in 1 mg / kg at speeds of 25-50 mg / min, 5 min possible re-introduction of (total dose should not exceed 3 mg / kg) if necessary, switch to the introduction of infusion at 30 mg / kg / min, maximum daily dose for children is determined by weighing the child and makes up 4-5 mg / kg for children aged 3 years for local anesthesia (conduction, infiltration, terminal, spinal) dose, which injected a large extent depends on the application, with local anesthesia - anesthesia for use 5-10 ml of 2% of the district; anesthesia for fingers - 2-3 ml of 2% of the district, for shoulder pain and sacral plexus - 5-10 ml of 2% of the district, children up to 2 years are used for surface anesthesia prior bedclothes having put cotton swabs, children and elderly patients correcting the dose according bedclothes age and here condition; spray applied to children of 8 years.
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