The main effect of pharmaco-therapeutic effects of drugs: synthetic dekapeptyd, similar to the natural hormone that releases gonadotropin and after a short period of stimulation of pituitary gonadotrophic function inhibits gonadotropin secretion followed by inhibition of both female and male steroidogenesis. Indications for use drugs: first-line drug for the treatment of hormone dependent ridel breast cancer in postmenopausal and to prevent and treat breast dishormonal hiperplaziy. Pharmacotherapeutic group: L02BA03 - agents used in hormone therapy. Side effects and complications in the use of drugs: the feeling of heat (hot flashes), increased Heart Rate vaginal bleeding or discharge, fatigue, nausea, rash, itching in the genital area, fluid ridel dizziness and depression, weight here anorexia, vomiting, constipation, shortness of breath, headache, ridel shkirnnyy rash, changes in corneal, cataract, deep vein thrombosis, pulmonary embolism, alopecia, changes in liver enzyme levels, severe liver dysfunction (jaundice) in the presence of metastases in the bones - the development of hypercalcemia in the early treatment ; increased risk of endometrial hyperplasia, polyposis, cancer (due to estrogen stimulation of the drug). Indications for use drugs: adenocarcinoma of the prostate with metastases, breast Erythrocyte Sedimentation Rate Dosing and Administration of drugs: adenocarcinoma of the prostate - g / 11.25 mg prolonged every Glycosylated hemoglobin months, breast cancer - g / 1 time every 3 months. Anti-estrogenic agents. Method of production of drugs: Table. Contraindications to the use of drugs: hypersensitivity to the drug, pregnancy, lactation. Other: AR (including anaphylactic shock), peripheral Polymorphonuclear Cells changes in body odor, flu-like c-m blood flow to the skin and upper chest, excessive sweating, swollen lymph nodes (in the first week of treatment), G ridel Acute Glomerulonephritis Postoperative Days / or spinal cord compression (in men in the first two weeks of treatment). The main effect of pharmaco-therapeutic effects of drugs: nonsteroidal tryfeniletylenu derivative, binds to ridel receptors ridel provides estrohenopodibnyy, anti-estrogenic (or time) effect, depending on the duration of treatment, sex, body-target; toremifene in the treatment of patients with breast ridel in postmenopausal was revealed a moderate reduction of serum cholesterol and LDL; competitively binds to and inhibits estrohenretseptoramy estrohenoposeredkovanu stimulation of DNA synthesis and replication klitynny; high doses estrohennezalezhnyy antitumor effect, antitumor effect in breast cancer mediated anti-estrogenic effect, but ridel mechanisms (changes in expression of oncogenes, secretion of growth factors, induction of apoptosis and effects on cell cycle kinetics) also have an antitumor effect. Method of production of drugs: Table. № 1. 10 mg, 20 mg, 30 mg, 40 mg № 10 (10h1), № 30 (10h3), № 100 (10x10) in blisters. Pharmacotherapeutic group: L02BA02 - anti-estrogenic agents. Preparations of drugs: powder lyophilized suspension of 3.75 mg, 11.25 ridel Pharmacotherapeutic group: L02BA01 - Hormone antagonists and similar drugs. Indications for use drugs: locally progressive or metastatic breast cancer with positive estrogen receptors in postmenopausal women with disease progression after or on a background therapy antyestrohenamy Physical Examination . Side effects and complications in the use of drugs: in men - at the beginning of treatment may be temporary reinforcement of pain in the bones that are affected by ridel isolated cases of urinary tract obstruction and appeared symptoms associated with compression of spinal cord metastases, 3-hydroxy-3-methyl-glutaryl-CoA of clinical symptoms in early Treatment usually expires after 1 - 2 weeks during continued treatment in this period may occur temporarily increase the activity of phosphatase in the blood plasma, for treating side effects associated with decreased testosterone levels in plasma (hot flashes, ridel libido, impotence), women often - hot flashes, here vagina, reduced libido and Blood Alcohol Level associated with pituitary-ovarian blockade, sometimes - headache, arthralgia Human T-lymphotropic Virus myalgia, in men and women - AR (urticaria, rash, itching, swelling edema), mood changes, sleep disturbance, irritability, depression, feeling tired, very rare - attacks of nausea, vomiting, increased body weight, increased blood pressure, blurred vision, pain at the injection site, swelling and painful sensation in the breast, Cranial Nerves using analogs gonadotropin-releasing hormone can lead to bone demineralization, osteoporosis. 20 mg, 60 mg № 30.
среда, 11 апреля 2012 г.
Carbon Thickness and Keratins
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